Wenwei Lin
Name Wenwei Lin
Email wenweilin@ntnu.edu.tw
Office Tel No. (02)77496131
Title Outstanding Professor
Research Synthetic Methodology, Asymmetric Organic Catalysis
Research Specialization Organic Synthesis, Asymmetric Organic Catalysis
Student Postdoc.: Dr. 陳奕儒, Dr.  Gangababu Marri。
Ph.D students: 吳佩珊, Durga Prasad Gurram, Raghunath Maruti Walunj, Ganesh Shantaram Khomane, Naveen Jothimani。
Master students: 劉家慶, 施承均, 陳佑杰, 陳彥愷, 陳俞瑄, 潘柏瑄, 陳沂禎, 余如音, 張嘉讌。
  1. Chien, P.-C.; Chen, Y.-J.; Marri, G.; Chen, Y.-R.; Chang, C.-F.; Lin, W.* "Syntheses of β-Acylated Alkylidene Indandiones and Furo[2,3-f]dibenzotropones via MBH-type Annulation/acylation or Wittig Reaction" J. Chin. Chem. Soc. 2024, accepted.
  2. Gurram, P. D.; Marri, G.; Jothimani, N.; Lin, W.* "Diversity-Oriented Synthesis of Chromone Inden-1-one Fused Cyclopentadienylides and C-Acylated Chromone Adducts via Allylic Phosphorus Ylides" Chem. Commun. 2024, 60, 9817-9820.參考連結
  3. Chen, Y.-R.; Marri, G.; Lin, W.* "The Integral Role of Conjugate Acids in Brønsted Base-Catalyzed Regiodivergent Synthesis" ChemCatChem 2024, 16, e202400405.參考連結
  4. Chien, P.-C.; Chen, Y.-R.; Chen, Y.-J.; Chang, C.-F.; Marri, G.; Lin, W.* "Synthesis of Furo[2,3-f]dibenzotropones via Intramolecular Wittig Reaction of Alkylidene Dibenzo-β-tropolones" Adv. Synth. Catal. 2024, 366, 420-425.參考連結
  5. Liou, Y.-C.; Chen, Y.-R.; Hsu, C.-W.; Huang, X.-R.; Wang, H.-W.; Lin, W.* "Alkylidene Meldrum's Acid as Acceptor-Donor-Acceptor Substrate for Organocatalytic Asymmetric (3+2) Cycloaddition/Annulation Reaction" Adv. Synth. Catal. 2023, 365, 3603-3610.參考連結
  6. Wu, P.-S.; Liou, Y.-C.; Marri, G.; Chen, Y.-R.; Wu, J.-R.; Lin, W.* "Synthesis of Chromeno[4,3-b]pyrrolidines from Azomethine Ylides and Vinyl para-Quinone Methides via (3+2) Cycloaddition/oxa-1,6-addition" J. Chin. Chem. Soc. 2023, 70, 2136-2146.參考連結
  7. Lung, T.-H.; Chen, Y.-R.; Chang, C.-L.; Jeng, W.-C.; Wu, P.-S.; Vagh, S.; Marri, G.; Lin, Y.-F.; Lin, W.* "Diversity-Oriented Synthesis of Spiro- and 3-Methylene-hydroquinone-Indandiones via an Organobase-Controlled Cascade Strategy" Adv. Synth. Catal. 2023, 365, 1391-1397.參考連結
  8. Vagh, S.; Hou, B.-J.; Edukondalu, A.; Wang, P.-C.; Chen, Y.-R.; Lin, W.* "Phosphine-Mediated Rauhut-Currier-Type/Acyl Transfer/ Wittig Strategy for Synthesis of Spirocyclopenta[c]chromene-Indolinones" Adv. Synth. Catal. 2021, 363, 5429-5435.參考連結
  9. Khairnar, P.; Su, Y.-H.; Edukondalu, A.; Lin, W.* "Enantioselective Synthesis of Spiropyrazolone-Fused Cyclopenta[c]chromen-4-ones Bearing Five Contiguous Stereocenters via (3+2) Cycloaddition" J. Org. Chem. 2021, 86, 12326-12335參考連結
  10. Jeng, W.-C.; Chien, P.-C.; Vagh, S.; Edukondalu, A.; Lin, W.* "Organophosphane-Catalyzed Construction of Functionalized 2-Ylideneoxindoles via Direct β-Acylation" Synthesis 2021, 53, 4409-4418參考連結
  11. Liou, Y.-C.; Wang, H.-W.; Edukondalu, A.; Lin, W.* "Phosphine-Catalyzed Chemoselective Reduction/Elimination/Wittig Sequence for Synthesis of Functionalized 3-Alkenyl Benzofurans" Org. Lett. 2021, 23, 3064-3069.參考連結
     
  12. Edukondalu, A.; Vagh, S.; Lin, T.-H.; Lin, W.* "Construction of Indeno[1,2-b]pyrroles via Chemoselective N‒Acylation/Cyclization/Wittig Reaction Sequence" Chem. Commun. 2021, 57, 2045-2048.參考連結
  13. Vagh, S.; Hou, B.-J.; Edukondalu, A.; Wang, P.-C.; Lin, W.* "Phosphine-Mediated MBH-Type/Acyl Transfer/Wittig Sequence for Construction of Functionalized Furo[3,2-c]coumarins" Org. Lett. 2021, 23, 842-846.參考連結
  14. Huang, C.-C.; Chang, K.-H.; Chiu, Y.-J.; Chen, Y.-R.; Lung, T.-H.; Hsieh-Li, H.-M.; Su, M.-T.; Sun, Y.-C.; Chen, C.-M.*; Lin, W.*; Lee-Chen, G.-J.* "Multi-target effects of novel synthetic coumarin derivatives protecting Aβ-GFP SH-SY5Y cells against Aβ Toxicity" Cells 2021, 10, 3095.參考連結
  15. Chiu, Y.-J.; Lin, T.-H.; Chen, C.-M.; Lin, C.-H.; Teng, Y.-S.; Lin, C.-Y.; Sun, Y.-C.; Hsieh-Li, H.-M.; Su, M.-T.; Lee-Chen, G.-J.*; Lin, W.*; Chang, K.-H.* "Novel Synthetic Coumarin-Chalcone Derivative (E)-3-(3-(4-(Dimethylamino)Phenyl)Acryloyl)-4-Hydroxy-2H-Chromen-2-One Activates CREB-Mediated Neuroprotection in Aβ and Tau Cell Models of Alzheimer's DiseaseOxid. Med. Cell. Longev. 2021, 2021, 3058861. 參考連結
  16. Khairnar, P.; Su, Y.-H.; Chen, Y.-C.; Edukondalu, A.; Chen, Y.-R.; Lin, W.* "Organophosphane-Catalyzed Direct β-Acylation of 4-Arylidene Pyrazolones and 5-Arylidene Thiazolones with Acyl Chlorides" Org. Lett. 2020, 22, 6868-6872.參考連結
  17. Wang, M.; Tseng, P.-Y.; Chi, W.-J.; Suresh, S.; Edukondalu, A.; Chen, Y.-R.; Lin, W.* "Diversity-Oriented Synthesis of Spirocyclohexene Indane-1,3-diones and Coumarin-Fused Cyclopentanes via an Organobase-Controlled Cascade Reaction" Adv. Synth. Catal. 2020362, 3407-3415. 參考連結
  18. Khairnar, P.; Wu, C.-Y.; Lin, Y.-F.; Edukondalu, A. Chen, Y.-R.; Lin, W.* "Diversity-Oriented Synthesis of Spiropentadiene Pyrazolones and 1-H-Oxepino[2,3-c]pyrazoles from Doubly Conjugated Pyrazolones via Intramolecular Wittig Reaction" Org. Lett. 202022, 4760-4765. 參考連結
  19. Vagh, S. S.; Karanam, P.; Liao, C.-C.; Lin, T.-H.; Liou, Y.-C.; Edukondalu, A.; Chen, Y.-R.; Lin, W.* "Enantioselective Construction of Spirooxindole-Fused Cyclopenta[c]chromen-4-ones Bearing Five Contiguous Stereocenters via a Stepwise (3+2) Cycloaddition" Adv. Synth. Catal. 2020362, 1679-1685. 
     
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  20. Liou, Y.-C.; Su, Y.-H.; Ku, K.-C.; Edukondalu, A.; Lin, C.-K.; Ke, Y.-S.; Karanam, P.; Lee, C.-J.; Lin, W.* "Organophosphane-Promoted Synthesis of Functionalized α,β-Unsaturated Alkenes and Furanones via Direct β-Acylation" Org. Lett. 201921, 8339-8343.
     
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  21. Liou, Y.-C.; Karanam, P.; Jang, Y.-J.; Lin, W.* "Synthesis of Functionalized Benzofurans from para-Quinone Methides via Phospha-1,6-Addition/O-acylation/Wittig Pathway" Org. Lett. 201921, 8008-8012. 參考連結
  22. Khairnar, P.; Lung, T.-H.; Lin, Y.-J.; Wu, C.-Y.; Koppolu, S.; Edukondalu, A.; Karanam, P.; Lin, W.* "An Intramolecular Wittig Approach toward Heteroarenes: Synthesis of Pyrazoles, Isoxazoles, and Chromenone-oximes" Org. Lett. 201921, 4219-4223. 
     
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  23. Yang, S.-M.; Karanam, P.; Wang, M.; Jang, Y.-J.; Yeh, Y.-S.; Tseng, P.-Y.; Reddy, G. M.; Liou, Y.-C.; Lin, W.* "A Vinylogous Michael Addition-Triggered Quadruple Cascade Reaction for the Enantioselective Generation of Multiple Quaternary Stereocenters" Chem. Commun. 201955, 1398-1401. 參考連結
  24. Karanam, P.; Reddy, G. M.; Lin, W.* "Strategic Exploitation of Wittig Reaction: Facile Synthesis of Heteroaromatics and Multifunctional Olefins" Synlett 201829, 2608-2622. 參考連結
  25. Lee, S.-Y.; Chiu, Y.-J.; Yang, S.-M.; Chen, C.-M.; Huang, C.-C.; Lee-Chen, G.-J.*; Lin, W.*; Chang, K.-H.* "Novel Synthetic Chalcone–coumarin Hybrid for Aβ Aggregation Reduction, Antioxidation, and NeuroprotectionCNS Neurosci. Ther. 201824, 1286-1298. 參考連結
  26. Chen, Y.-R.; Reddy, G. M.; Hsieh, K.-H.; Chen, K.-H.; Karanam, P.; Vagh, S. S.; Liou, Y.-C.; Lin, W.* "3-Homoacyl coumarin: an all carbon 1,3-dipole for enantioselective concerted (3+2) cycloaddition" Chem. Commun. 201854, 12702-12705. 參考連結
  27. Yu, J.-K.; Chien, H.-W.; Lin, Y.-J.; Karanam, P.; Chen, Y.-H.; Lin, W.* "Diversity-oriented synthesis of chromenopyrrolidines from azomethine ylides and 2-hydroxybenzylidene indandiones via base-controlled regiodivergent (3+2) cycloaddition" Chem. Commun. 201854, 9921-9924. 參考連結
  28. Yang, S.-M.; Wang, C.-Y.; Lin, C.-K.; Karanam, P.; Reddy, G. M.; Tsai, Y.-L.; Lin, W.* "Diversity-Oriented Synthesis of Furo[3,2-c]coumarins and Benzofuranyl Chromenones via Chemoselective Acylation/Wittig Reaction" AngewChemIntEd201857, 1668-1672; AngewChem2018130, 1684-1688. 參考連結
  29. Karanam, P.; Reddy, G. M.; Koppolu, S. R.; Lin, W.* "Recent topics of phosphine-mediated reactions" Tetrahedron Lett201859, 59-76. 參考連結
  30. Yang, S.-M.; Tsai, Y.-L.; Reddy, G. M.; Moehlmann, L.; Lin, W.* "Chemo- and diastereoselective Michael-Michael-acetalization cascade for the synthesis of 1,3-indandione-fused spiro[4.5]decan scaffolds" J. Org. Chem. 201782, 9182-9190. 參考連結
  31. Yang, S.-M.; Reddy, G. M.; Wang, T.-P.; Yeh, Y.-S.; Wang, M.; Lin, W.* "An Enantioselective Cascade for Simultaneous Generation of Five Quaternary Stereocenters from Fully Substituted Enones" Chem. Commun. 201753, 7649-7652. 參考連結
  32. Chen, Y.-R.; Reddy, G. M.; Hong, S.-H.; Wang, Y.-Z.; Yu, J.-K.; Lin, W.* "Four-component synthesis of phosphonium salts: application toward an alternative approach to cross-coupling for the synthesis of bis-heteroarenes" Angew. Chem. Int. Ed. 201756, 5106-5110; Angew. Chem. 2017129, 5188-5192.  參考連結
  33. Yang, S.-M.; Reddy, G. M.; Liu, M.-H.; Wang, T.-P.; Yu, J.-K.; Lin, W.* "Diastereoselective Synthesis of Rauhut-Currier-Type Adducts via An Unexpected α-Addition of α,β-Unsaturated r-Butyrolactams to Coumarin Derivatives" J. Org. Chem. 201782, 781-789. 參考連結
  34. Chang, G.-H.; Wang, C.-Y.; Reddy, G. M.; Tsai, Y.-L.; Lin, W.* "Enantioselective synthesis of polysubstituted benzopyrano[3,4-c]pyrrolidine frameworks via [3+2] cycloaddition of azomethine ylides and coumarin derivatives" J. Org. Chem. 201681, 10071-10080. 參考連結
  35. Lee, C.-J.; Chang, T.-H.; Yu, J.-K.; Reddy, G. M.; Hsiao, M.-Y.; Lin, W.* "Synthesis of functionalized furans via chemoselective reduction/Wittig reaction using catalytic triethylamine and phosphine" Org. Lett. 201618, 3758-3761. 參考連結
  36. Reddy, G. M.; Ko, C.-T.; Hsieh, K.-H.; Lee, C.-J.; Das, U.; Lin, W.* "Expanding the scope of primary amine catalysis: Highly stereoselective synthesis of indanedione-fused 2,6-disubstituted trans-spirocyclohexanones" J. Org. Chem. 201681, 2420-2431. 參考連結
  37. Moehlmann, L.; Chang, G.-H.; Reddy, G. M.; Lee, C.-J.; Lin, W.* "Organocatalytic enantioselective synthesis of tetrahydrofluoren-9-ones via vinylogous Michael addition/Henry reaction cascade of 1,3-indandione-derived pronucleophiles" Org. Lett. 201618, 688-691. 參考連結
  38. Lee, C.-J.; Tsai, C.-C.; Hong, S.-H.; Chang, G.-H.; Yang, M.-C.; Moehlmann, L.; Lin, W.* "Preparation of Furo[3,2-c]coumarins from 3-Cinnamoyl-4-hydroxy-2H-chromen-2-ones and Acyl Chlorides: A Bu3P-Mediated C-Acylation/Cyclization Sequence" Angew. Chem. Int. Ed. 201554, 8502-8505; Angew. Chem. 2015127, 8622-8625. 參考連結
  39. Tsai, Y.-L.;  Lin, W.* "Synthesis of multifunctional alkenes from substituted acrylates and aldehydes via phosphine-catalyzed Wittig reaction" Asian J. Org. Chem. 2015, 4, 1040-1043. 參考連結
  40. Chen, C.-H.; Ko, C.-T.; Reddy, G. M.; Lee, C.-J.; Lin, W.* "An enantioselective synthesis of substituted cyclohexanone derivatives with an all-carbon quaternary stereocenter by using an organocatalytic asymmetric domino double Michael addition" Eur. J. Org. Chem. 2015, 5254-5265. 參考連結
  41. Jang, Y.-J.; Chen, Y.-S.; Lee, C.-J.; Chen, C.-H.; Reddy G. M.; Ko, C.-T.; Lin, W.* "Asymmetric organocatalytic synthesis of highly substituted cyclohexenols via domino double Michael reactions of 1-hydroxy-1,4-dien-3-ones and 2-alkylidene malononitirles" Eur. J. Org. Chem. 2015, 2066-2074. 參考連結
  42. Chen, Y.-R.; Das, U.; Liu, M.-S.; Lin, W.* "Organocatalytic Enantioselective Direct Vinylogous Michael Addition of alpha,belta-Unsaturated gamma-Butyrolactam to belta-Acyl Acrylates and 1,2-Diacylethylenes” J. Org. Chem. 2015, 80, 1985-1992. 參考連結
  43. Jang, Y.-J.; Chen, Y.-S.; Lee, C.-J.; Chen, C.-H.; Lin, W.* "Base-Catalyzed Domino Double Michael Reactions of 1-Hydroxy-1,4-dien-3-ones and 2-Alkylidene Malononitirles: A Diastereoselective Route to Polysubstituted 4-Hydroxy-3-keto-cyclohex-3-ene” Synthesis 201547, 95-107. 參考連結
  44. Fan, Y.-S.; Das, U.; Hsiao, M.-Y.; Liu, M.-S.; Lin, W.* "Chemoselective Intramolecular Wittig Reactions for the Synthesis of Oxazoles and Benzofurans” J. Org. Chem. 201479, 11567-11582. 參考連結
  45. Das, U.; Tsai, Y.-L.; Lin, W.* "Preparation of functionalized heteroaromatics using intramolecular Wittig reaction" Org. Biomol. Chem. 201412, 4044-4050. (Perspective) (This article is part of the themed collection: 2014 Hot Articles in Organic and Biomolecular Chemistry參考連結
  46. Tsai, Y.-L.; Syu, S.; Yang, S.-M.; Das, U.; Fan, Y.-S.; Lee, C.-J.; Lin, W.* "Synthesis of Multi-Functional Alkenes via Wittig Reaction with a New-Type of Phosphorus Ylides” Tetrahedron 2014, 70, 5038-5045參考連結
  47. Lee, C.-J.; Sheu, C.-N.; Tsai, C.-C.; Wu, Z.-Z.; Lin, W.* "Direct  β-Acylation of 2-Arylidene-1,3-indandiones with Acyl Chlorides Catalyzed by Organophosphanes” Chem. Commun. 201450, 5304-5306.(Featured in "Emerging investigators" issue 2014) 參考連結
  48. "Contributors to the Emerging Investigators Issue 2014", Chem. Commun. 201450, 5100-5114. 參考連結
  49. Lee, Y.-T.; Das, U.; Chen, Y.-R.; Lee, C.-J.; Chen, C.-H.; Yang, M.-C.; Lin, W.* "Enantioselective Synthesis of Coumarin Derivatives Catalyzed by Primary Amine" Adv. Synth. Catal. 2013355, 3154-3160. 參考連結
  50. Tsai, Y.-L.; Fan, Y.-S.; Lee, C.-J.; Huang, C.-H.; Das, U.; Lin, W.* "An Efficient Synthesis of Trisubstituted Oxazoles via Chemoselective O-Acylations and Intramolecular Wittig Reactions" Chem. Commun. 201349, 10266-10268. 參考連結
  51. Lee, Y.-T.; Lee, Y.-T.; Lee, C.-J.; Sheu, C.-N.; Lin, B.-Y.; Wang, J.-H.*; Lin, W.* "Chemoselective Synthesis of Tetrasubstituted Furans via Intramolecular Wittig Reactions: Mechanism and Theoretical Analysis" Org. Biomol. Chem. 201311, 5156-5161. 參考連結
  52. Tsai, Y.-L.; Das, U.; Syu, S.; Lee, C.-J.; Lin, W.* "Facile synthesis of functional tricyclic fused furans via intramolecular Wittig reactions" Eur. J. Org. Chem. 2013, 4634-4641參考連結
  53. Das, U.; Chen, Y.-R.; Tsai, Y.-L.; Lin, W.* "Organocatalytic enantioselective direct vinylogous Michael addition of r-substituted butenolides to 3-aroyl acrylates and 1,2-diaroylethylenes"Chem. Eur. J. 201319, 7713-7717. 參考連結
  54. Wu, Z.-Z.; Jang, Y.-J.; Lee, C.-J.; Lee, Y.-T.; Lin, W.* "A Versatile and Practical Method for Regioselective Synthesis of Polysubstituted Furanonaphthoquinones" Org. Biomol. Chem. 201311, 828-834. (HOT article) 參考連結
  55. Das, U.; Tsai, Y.-L.; Lin, W.* "An efficient organocatalytic enantioselective synthesis of spironitrocyclopropanes" Org. Biomol. Chem. 201311, 44-47. (HOT communication) 參考連結
  56. Lee, Y.-T.; Jang, Y.-J.; Syu, S.; Chou, S.-C.; Lee, C.-J.; Lin, W.* “Preparation of Functional Benzofurans and Indoles via Chemoselective Intramolecular Wittig Reactions" Chem. Commun. 201248, 8135-8137. 參考連結
  57. Das, U.; Huang, C.-H.; Lin, W.* "Enantioselective synthesis of substituted pyrans via amine-catalyzed Michael addition and subsequent enolization/cyclisation" Chem. Commun. 201248, 5590-5592. (Featured in "Organocatalysis" Web-themed issue) 參考連結
  58. Lee, C.-J.; Jang, Y.-J.; Wu, Z.-Z. ; Lin, W.* "Preparation of Functional Phosphorus Zwitterions from Activated Alkanes, Aldehydes, and Tributylphosphine: Synthesis of Polysubstituted Furo[3,2-c]coumarins" Org. Lett. 201214, 1906-1909. 參考連結
  59. Jang, Y.-J.; Syu, S.; Jhang, Y.-W.; Lee, Y.-T.; Lee, C.-J.; Chen, K.-W.; Das, U.; Lin, W.* "Tandem three-component reactions of aldehyde, alkyl acrylate, and dialkylmalonate catalyzed by ethyl diphenylphosphine" Molecules 201217, 2529-2541. 參考連結
  60. Syu, S.; Huang, C.-H.; Chen, K.-W.; Lee, C.-J.; Das, U.; Jang, Y.-J.; Lin, W.* "Enantioselective organocatalytic Michael addition of ketones to alkylidene malonates"Chirality 201224, 600-605參考連結
  61. Jang, Y.-J.; Syu, S.; Chen, Y.-J.; Yang, M.-C.; Lin, W.* "Syntheses of Furo[3,4-c]coumarins and Related Furyl Coumarin Derivatives via Intramolecular Wittig Reactions" Org. Biomol. Chem. 201210, 843-847. 參考連結
  62. Syu, S.; Lee, Y.-T.; Jang, Y.-J.; Lin, W.* "Preparation of Functional Benzofurans, Benzothiophenes, and Indoles Using Ester, Thioester, and Amide via Intramolecular Wittig Reactions" Org. Lett. 201113, 2970-2973. 參考連結
  63. Syu, S.; Lee, Y.-T.; Jang, Y.-J.; Lin, W.* "Organocatalytic tandem three-component reaction of imine, alkyl vinyl ketone, and imide via aza-Baylis-Hillman reaction" J. Org. Chem. 201176, 2888-2891. 參考連結
  64. Chen, K.-W.; Syu, S.; Jang, Y.-J.; Lin, W.* "A facile approach to highly functional trisubstituted furans via intramolecular Wittig reactions"Org. Biomol. Chem. 20119, 2098-2106. 參考連結
  65. Wang, D.-W.; Syu, S.; Hung, Y.-T.; Chen, P.; Lee, C. J.; Chen, K.-W.; Chen, Y.-J.; Lin, W.* "Organocatalytic Tandem Three-Component Reaction of Aldehyde, Alkyl Vinyl Ketone, and Amide: One-Pot Syntheses of Highly Functional Alkenes"Org. Biomol. Chem. 20119, 363-366. 參考連結
  66. Syu, S.; Wang, D.-W.; Chen, P.; Hung, Y.-T.; Jhang, Y.-W.; Kao, T.-T.; Lee, Y.-T.; Lin, W.* "Tandem Three-Component Reaction of Aldehyde, Alkyl Acrylate and Amide Using Ethyl Diphenylphosphine as Organocatalyst" Tetrahedron Lett. 201051, 5943-5946.
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  67. Kao, T.-T.; Syu, S.; Jhang, Y.-W.; Lin, W.* "Preparation of Tetrasubstituted Furans via Intramolecular Wittig Reactions with Phosphorus Ylides as Intermediates", Org. Lett. 201012, 3066-3069. 參考連結
  68. Syu, S.; Kao, T.-T.; Lin, W.* "A New Type of Organocatalyst for Highly Stereoselective Michael Addition of Ketones to Nitroolefins on Water", Tetrahedron 201066, 891–897. 參考連結
  69. Lin, W.; Chen, L.; Knochel, P.* "Preparation of Functionalized 3,4-Pyridynes via 2-Magnesiated Diaryl Sulfonates", Tetrahedron 200763, 2787-2797.
  70. Lin, W.; Ilgen, F.; Knochel, P.* "Preparation of Highly Functionalized Arylmagnesium Reagents by the Addition of Magnesium Phenylselenide to Arynes", Tetrahedron Lett2006, 47, 1941-1944.
  71. Lin, W.; Baron, O.; Knochel, P.* "Highly Functionalized Benzene Syntheses by Directed Mono or Multiple Magnesiations with TMPMgCl‧LiCl", Org. Lett. 20068, 5673-5676.
  72. Sapountzis, I.; Lin, W.; Kofink, C. C.; Despotopoulou, C.; Knochel, P.* "Iron-Catalyzed Aryl-Aryl Cross-Couplings with Magnesium-Derived Copper Reagents", Angew. Chem. Int. Ed. 200544, 1654-1657. Angew. Chem. 2005117, 1682-1685.
  73. Lin, W.; Sapountzis, I.; Knochel, P.* "Preparation of Functionalized Aryl Magnesium Reagents by the Addition of Magnesium Aryl Thiolates and Amides to Arynes", Angew. Chem. Int. Ed. 200544, 4258-4261. Angew. Chem. 2005117, 4330-4333.
  74. Sapountzis, I.; Lin, W.; Fischer, M.; Knochel, P.* "Preparation of Polyfunctional Arynes via 2-Magnesiated Diaryl sulfonates", Angew. Chem. Int. Ed. 200443, 4364-4366. Angew. Chem. 2004116, 4464-4466.
  75. Jang, Y.-J.; Lin, W.-W.; Shih, Y.-K.; Liu, J.-T.; Hwang, M.-H.; Yao, C.-F.* "An Easy One-Pot Method for the Synthesis of 2,2-Disubstituted 1-Nitroalkenes", Tetrahedron 200359, 4979-4992.
  76. Lin, W.-W.; Jang, Y.-J.; Wang, Y.; Liu, J.-T.; Hu, S.-R.; Wang, L.-Y.; Yao, C.-F.* "An Improved and Easy Method for the Preparation of 2,2-Disubstituted 1-Nitroalkenes", J. Org. Chem. 200166, 1984-1991.
  77. Liu, J.-T; Lin, W.-W.; Jang, J.-J.; Liu, J.-Y.; Yan, M.-C.; Hung, C.; Kao, K.-H.; Wang, Y.; Yao, C.-F.* "One-pot synthesis of six- or five-membered carbocycles through intramolecular cycloadditions by the use of ethyl chloroformate", Tetrahedron 199955, 7115-7128.
  78. Yan, M.-C.; Liu, J.-Y.; Lin, W.-W.; Kao, K.-H.; Liu, J.-T; Jang, J.-J.; Yao, C.-F.* "One-Pot Synthesis of Five-Membered Cyclic Thioethers or Ethers via Intramolecular Nitrile Oxide-Olefin Cycloaddition (INOC) or Intramolecular Alkoxycarbonyl Nitronate-Olefin Cycloaddition (IAOC) by the use of Methyl Chloroformate", Tetrahedron 199955, 12493-12514.
  79. Lee-Chen, G.-J.; Lin, W. "Method for Treating Abnormal B-Amyloid Aggregation Mediated Diseases" 2018, United States Patent (Publication Number:  US 2018/0042864A1).
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